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Description: Axolotl - the Mexican wonder healerResearch Field: Developmental and Evolutionary Biology/GeneticsA Mexican salamander is the world champion in regeneration. This primeval animal, called the axolotl, doesn’t care if one of its legs gets ripped off - as it will grow back in a matter of days. The same holds true for a lost tail, a part of its jaw, an eye, or even a piece of its heart.A team of scientists headed by Elly Tanaka at the Max Planck Institute for Cell Biology and Genetics in Dresden is taking a closer look at this astounding phenomenon. Their hope is to unveil the secrets of the axolotl for the benefit of mankind. After all, human beings are also capable of regenerating to a certain extent - for example, wound healing. The researchers believe that humans lost the ability to completely regenerate during the course of evolution. It is, however, possible that this ability has only been suppressed and could somehow be reactivated in the future.The researchers have already discovered the first messengers that reprogram cells in axolotls, allowing muscle or cartilage cells to be produced from nerve cells. However, it may still take decades until the results can also be applied to human beings. The Mexican salamander is therefore assured its status as world champion regenerator for years to come.Copyright: © Deutsche WellePublished at ScienceStage.com in cooperation with the Max Planck Society.Involved Institutes: Max Planck Institute of Molecular Cell Biology and Genetics
Abstract: MRC Centre for Developmental Neurobiology, King's College London, London, UK.
Abstract: Laboratoire de Biologie et G?n?tique du D?velopement, URA CNRS 256, Universit? de Rennes I, France.
Abstract: The glossopharyngeal nerve of the axolotl labeled with carbocyanine dye (diI). Nagai T, Oka Y. Department of Physiology, Teikyo University School of Medicine, Tokyo, Japan. Fluorescent carbocyanine dye (diI) was used to label the glossopharyngeal ...
Abstract: Ectopic expression of a genomic fragment containing a homeobox causes neural defects in the axolotl. Whiteley M, Armstrong JB. Department of Biology, University of Ottawa, Ont., Canada. An axolotl (Ambystoma mexicanum) genomic fragment containing ...
Abstract: T-cell-specific membrane antigens in the Mexican axolotl (urodele amphibian). Kerfourn F, Guillet F, Charlemagne J, Tournefier A. Laboratoire d'Immunologie Compar?e, Universit? Pierre et Marie Curie, CNRS URA 1135, Paris, France. Comparative analy...
Abstract: Transient developmental expression of IgY and secretory component like protein in the gut of the axolotl (Ambystoma mexicanum). Fellah JS, Iscaki S, Vaerman JP, Charlemagne J. Laboratoire d'Immunologie Compar?e, Universit? Pierre et Marie Curie, Pa...
Abstract: Department of Developmental and Cell Biology and The Developmental Biology Center, University of California Irvine, Irvine, CA 92697-2305, USA.
Abstract: A light and electron microscopic study of the development of the Mauthner cell and vestibular nerve in the axolotl. Leber SM, Model PG. Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461. Vestibular axons form s...
Abstract: Laboratorio de Ecofisiolog?a, Universidad Nacional Aut?noma de M?xico, M?xico DF 04510, Mexico.
Abstract: Evidence for enkephalin- and endorphin-immunoreactive cells in the anterior pituitary of the axolotl Ambystoma mexicanum. Leon-Olea M, Sanchez-Alvarez M, Pi?a AL, Bayon A. Divisi?n de Investigaciones en Neurociencias, Instituto Mexicano de Psiquiat...
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