Machu Picchu and The Sacred Valley - Part One

John and Cara take the train from Cuzco along the Sacred Valley to Aguas Calient...

Haunting music performed and composed by Shenkar and Michael Perfitt with photog...

symbol of the Inca Empire. Since 1983 the site has been designated as a United N...

The sacred city of Machu Picchu (in Quechua: old mountain) is the greatest Inca ...

Machu Picchu - "The Lost City of the Incas". 50 miles northwest of Cusco, Peru. ...

GIRLS DATING TOUR LATIN TRAVEL. SEYX PERUVIAN WOMEN, LADIES FROM LIMA PERU. PARQ...

Perú país de los INCAS. Perú Land of the Inkas. Perù Paese degli Incas. Pe...

Cusco Peru

referred to as "The Lost City of the Incas". Since 1983 the site has been design...

Disclaimer: This movie is considered to be in the public domain as defined by US...

Hitler gives a speech, but not on the war, but on some more personal issues!

Adolf Hitler

Part Two. The Periodic Table Song!!! A real gem that i've only ever heard on this programme. Maybe a...

More than 80 pictures taken during The Battle of Berlin in April-May 1945 (virtual photo album). Fir...

Nassim Haramein has dedicated his life to the study of planetary and hyperdimensional physics, dimen...

fragmentos, meteoros ou cristais de gelo, dado que freqüentemente demonstram trajetória que indica...

Must see video about the recently found legendary Labyrinth of Egypt. Could this be the most importa...

Winston Churchill's Inspirational Speech. Speeches that rallied an entire nation to defend their isl...

Lecture 2 of Leonard Susskind's Modern Physics course concentrating on Quantum Mechanics. Recorded J...

8277 Machu-Picchu is a main belt asteroid with an orbital pe...

Samlar machu ([is the Khmer] term for a category of [[sour (...

Catupecu Machu is an Argentine rock band, usually classified...

Author: J Kushner

Abstract:

Author: John W Rutledge

Abstract: The decorative bronze handle of a tumi excavated at the Inca city of Machu Picchu, Peru, contains 18 percent bismuth and appears to be the first known example of the use of bismuth with tin to make bronze. The alloy is not embrittled by the bismuth b...

Author: Irmgard Bauer

Abstract: Sexual and romantic relationships between local people and tourists have long taken place. Such encounters are not a modern phenomenon, but the potential of sexually transmitted infections (STIs), including HIV/AIDS, warrants greater research into th...

Author: M MACHU

Abstract:

Author: Tina K Machu

Abstract: Allosteric modulation of mouse 5-Hydroxytryptamine(3A) (5-HT(3A)) and 5-HT(3A/B) receptor function by ethanol and trichloroethanol (TCEt) was assessed in HEK293 cells with whole cell patch-clamp electrophysiological recordings. Ethanol enhanced 5-HT(...

Author: T K Machu

Abstract: The actions of colchicine were examined with the two-electrode voltage-clamp technique and radioligand binding assays in mouse and human 5-hydroxytryptamine(3A) receptors (5-HT(3A)Rs) expressed in Xenopus laevis oocytes. Colchicine inhibited 5-hydrox...

Author: J Machu

Abstract:

Author: T K Machu

Abstract: The present study examined the effects of bicuculline on the mouse 5-hydroxytryptamine(3A) receptor (5-HT(3A) receptor and the human alpha2 subunit of the glycine receptor. Bicuculline antagonized both the 5-HT(3A) receptor (IC(50)=20.12+/-0.39 micro...

Author: T K Machu

Abstract: Ligand-gated ion channel association with the cytoskeleton may play an important role in receptor distribution and function. However, the microtubule depolymerizing agent, colchicine, has inhibitory effects on glycine receptors that are independent o...

Author: T K Machu

Abstract: Molecular cloning of cDNAs coding for ligand-gated ion channel subunits makes it possible to study the pharmacology of recombinant receptors with defined subunit compositions. Many laboratories have used these techniques recently to study actions of ...

Author: T K Machu

Abstract: We examined the effects of several protein kinase C (PKC) inhibitors on the murine 5-hydroxytryptamine3 (5-HT3) receptor to determine whether they acted directly on the receptor. The 5-HT-evoked currents in Xenopus laevis oocytes expressing the recom...

Author: Dildy-Mayfield JE, Machu T, Leslie SW.

Abstract: Ethanol and voltage- or receptor-mediated increases in cytosolic Ca2+ in brain cells.
Dildy-Mayfield JE, Machu T, Leslie SW.
Division of Pharmacology, College of Pharmacy, University of Texas at Austin 78712.
Dissociated brain cells were isolated ...

Author: Dildy-Mayfield JE, Machu T, Leslie SW.

Abstract: Ethanol and voltage- or receptor-mediated increases in cytosolic Ca2+ in brain cells.
Dildy-Mayfield JE, Machu T, Leslie SW.
Division of Pharmacology, College of Pharmacy, University of Texas at Austin 78712.
Dissociated brain cells were isolated ...

Author: Tina K Machu

Abstract: The competitive antagonist d-tubocurarine (curare) has greater potency at mouse than at human 5-hydroxytryptamine 3A (5-HT3A) receptors, despite 84% amino acid sequence identity between the receptors. Within the ligand binding domain of this receptor...

Author: Tina K Machu

Abstract: Mutant 5-hydroxytryptamine (5-HT)3A receptors, in which changes were made at Ile294, position 16', of the second transmembrane domain, were assessed for alterations in macroscopic response kinetics and modulation by alcohols. Function of heterologous...

Author: Woodward JJ, Machu T, Leslie SW.

Abstract: Chronic ethanol treatment alters omega-conotoxin and Bay K 8644 sensitive calcium channels in rat striatal synaptosomes.
Woodward JJ, Machu T, Leslie SW.
Division of Pharmacology, University of Texas, Austin 78712.
Two groups of adult Sprague-Dawl...

Author: Tina K Machu

Abstract: The effects of phorbol 12-myristate, 13-acetate (PMA) on 5-hydroxytryptamine (5-HT)-evoked ion currents in the mouse 5-HT3A receptor were examined. Perfusion with PMA caused a concentration dependent potentiation of 5-HT mediated currents and increas...

Author: Leidenheimer NJ, Machu TK, Endo S, Olsen RW, Harris RA, Browning MD.

Abstract: Cyclic AMP-dependent protein kinase decreases gamma-aminobutyric acidA receptor-mediated 36Cl- uptake by brain microsacs.
Leidenheimer NJ, Machu TK, Endo S, Olsen RW, Harris RA, Browning MD.
Department of Pharmacology, University of Colorado Health...

Author: Machu TK, Olsen RW, Browning MD.

Abstract: Ethanol has no effect on cAMP-dependent protein kinase-, protein kinase C-, or Ca(2+)-calmodulin-dependent protein kinase II-stimulated phosphorylation of highly purified substrates in vitro.
Machu TK, Olsen RW, Browning MD.
Department of Pharmacol...