34 Sharpless Oxidation Catalysts and the Conformation of Cycloalkanes

Description: Freshman Organic Chemistry (CHEM 125) Professor Barry Sharpless of Scripps describes the Nobel prize-winning development of titanium-based catalysts for stereoselective oxidation, the mechanism of their reactions, and their use in preparing esomeprazole. Conformational energy of cyclic alkanes illustrates the use of molecular mechanics. Complete course materials are available at the Open Yale Courses website: open.yale.edu This course was recorded in Fall 2008.