Proline Kinks

Description: , forming a five-membered ring that includes the backbone nitrogen. This geometry severely limits the flexibility of the backbone. Because of this restricted conformational flexibility, many proline residues introduce sharp kinks into the path of a polypeptide backbone." Essential Cell Biology, Second Edition by Alberts, Bray, Hopkin, Johnson, Lewis, Raff, Roberts, Walter copyright 2004 by Garland Science Publishing ... Proline kink alpha amino acid helix polypeptide cell biology ...