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Fibroblast growth factors, or FGFs are a family of growth factors that are impor...
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Date: (16-11-09) Time: (00:52:35) |
Description:
Fibroblast growth factors, or FGFs are a family of growth factors that are important for normal embryonic development. There are over 20 members of the FGF family. Dr. John Rubenstein of UCSF explores several members of the FGF family, including FGF-8 and FGF-17, and discuss how these molecules are required for normal development of the cerebral cortex. He discusses FGFs that play a role in neocortical development, transcription factors that regulate FGF signaling in the cerebral cortex, and implications for autism spectrum disorders.
(UCTV #17662, first aired: 12/8/2009)
Abstract:
Toll-like receptor signaling alters the expression of regulator of G protein signaling proteins in dendritic cells: implications for G protein-coupled receptor signaling.
Shi GX, Harrison K, Han SB, Moratz C, Kehrl JH.
B Cell Molecular Immunology S...
Abstract: nt-to-point or point-to-multipoint signaling access . meta-signaling Sanjay Jha Signaling.7 Capability Set 2 . Variable bit rate . QoS indication by user . point-to-multipoint connections . multi-connection (per call) . negotiation and re-negotiation...
Abstract: nt-to-point or point-to-multipoint signaling access . meta-signaling Sanjay Jha Signaling.7 Capability Set 2 . Variable bit rate . QoS indication by user . point-to-multipoint connections . multi-connection (per call) . negotiation and re-negotiation...
Abstract: nt-to-point or point-to-multipoint signaling access . meta-signaling Sanjay Jha Signaling.7 Capability Set 2 . Variable bit rate . QoS indication by user . point-to-multipoint connections . multi-connection (per call) . negotiation and re-negotiation...
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Abstract: 3.6> Q.932 = Extends/uses Q.931 for supplementary services (call forwarding, etc) T Q.933 = Q.931 Extension/subset for Frame-relay T Signaling inside the network is more sophisticated than that between the network and the subscriber T Digital Subscri...
Abstract: 3.6> Q.932 = Extends/uses Q.931 for supplementary services (call forwarding, etc) T Q.933 = Q.931 Extension/subset for Frame-relay T Signaling inside the network is more sophisticated than that between the network and the subscriber T Digital Subscri...
Abstract: 3.6> Q.932 = Extends/uses Q.931 for supplementary services (call forwarding, etc) T Q.933 = Q.931 Extension/subset for Frame-relay T Signaling inside the network is more sophisticated than that between the network and the subscriber T Digital Subscri...
Abstract: Mice lacking the gene for suppressor of cytokine signaling 1 (SOCS1) show defective homeostasis of T lymphocytes due to accumulation of CD8(+) T cells, resulting at least partly from dysregulated IL-15 signaling. IL-15 alone does not stimulate prolif...
Abstract: Transmembrane signaling requires modular interactions between signaling proteins, phosphorylation or dephosphorylation of the interacting protein partners and temporary elaboration of supramolecular structures, to convey the molecular information fro...
Abstract: Whereas according to the neural default model, neural specification is induced by extracellular inhibitors of bone morphogenetic proteins (Bmps), the role of fibroblast growth factors (Fgfs) during neural induction is heavily debated. Here, we show t...
Abstract: SOCS1-/- mice die prematurely of increased interferon-gamma (IFNgamma) signaling with severe thymic atrophy and accelerated maturation of T cells. However, it was unclear whether the thymic defects were caused by SOCS1 deficiency or by increased IFNg...
Abstract: PURPOSE: XK469 (NSC 697887) is a novel antitumor agent with broad activity against a variety of tumors including drug-resistant tumors. Previous studies have indicated that XK469 is an antiproliferative agent with a low cytotoxic effect in human H116...
Abstract: Two reactive oxygen species (ROS), nitric oxide (NO(.)) and superoxide ((.)O2), contribute to persistent pain. Using three different animal models where ROS mediate pain, this study examined whether NO(.) and (.)O2 converge to peroxynitrite (ONOO(-))...
Abstract: Lipopolysaccharide (LPS) signals through Toll-like receptors (TLRs) in the course of sepsis, resulting in the release of inflammatory factors. In cell lines and murine models, parts of the signaling pathways involved have been elucidated with MyD88, ...
Abstract: Suppressor of cytokine signaling (SOCS) proteins are a family of Src homology 2-containing adaptor proteins. Cytokine-inducible Src homology domain 2-containing protein, SOCS1, SOCS2, and SOCS3 have been implicated in the down-regulation of cytokine ...
Abstract: Cilia have been implicated in Hedgehog (Hh) and Wnt signaling in mouse but not in Drosophila. To determine whether the role of cilia is conserved in zebrafish, we generated maternal-zygotic (MZ) oval (ovl; ift88) mutants that lack all cilia. MZovl mu...
Abstract: Prostate cancer is the most frequently diagnosed non-skin cancer and the third leading cause of cancer mortality in men. In the initial stages, prostate cancer is dependent on androgens for growth, which is the basis for androgen ablation therapy. Ho...
Abstract: