Botulinum Toxin: How to Correct the Complications and New Indications - Jose Marquez-Serres, MD, PhD

Dr. Gallagher specializes in movement disorders with special interests in young ...

Find out how researchers are engineering new pesticides. For more info read: env...

Enjoy a preview of this lecture given at the Defeat Autism Now Conference: Spons...

Enjoy a preview of this lecture given at the Defeat Autism Now Conference: Spons...

Enjoy a preview of this lecture given at the Defeat Autism Now Conference: Spons...

Enjoy a preview of this lecture given at the Defeat Autism Now Conference: Spons...

Enjoy a preview of this lecture given at the Defeat Autism Now Conference: Spons...

Enjoy a preview of this lecture given at the Defeat Autism Now Conference: Spons...

Enjoy a preview of this lecture given at the Defeat Autism Now Conference: Spons...

Enjoy a preview of this lecture given at the Defeat Autism Now Conference: Spons...

Robert H. Lustig, MD, UCSF Professor of Pediatrics in the Division of Endocrinology, explores the da...

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Dr. Christian Sandrock of UC Davis Divisions of Infectious Diseases and Pulmonary and Critical Care ...

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Botulinum toxin is a medication and a neurotoxic protein pro...

Botulinum toxin is a medication and a neurotoxic protein pro...

Botulinum toxin is a medication and a neurotoxic protein pro...

Clostridium botulinum is a Gram-positive, rod shaped bacteri...

Clostridium botulinum is a Gram-positive, rod shaped bacter...

The AB toxins are two-component protein complexes secreted b...

Alpha Toxin or alpha-toxin refers to several different prote...

Diphtheria toxin is an exotoxin secreted by Corynebacterium ...

Author: B R Dasgupta

Abstract:

Author: J C Martinez-Castrillo

Abstract: Most of the initial reports on botulinum toxin in tension-type headache (TTH) and in migraine were positive. Unfortunately, these results were not reproduced in well-designed, randomized controlled trials. So far, doses from 20 U (Botox) to 500 U (Dy...

Author: Hans Bigalke

Abstract: In some patients treated with botulinum toxin type A (BT) therapy failure occurs due to the formation of antibodies against BT (BT-AB). We investigated whether increased BT doses can overcome this form of therapy failure. Eight patients with cervical...

Author: U FLECK

Abstract:

Author: J P Lee

Abstract: INTRODUCTION: Long-term ocular alignment can be difficult to achieve in patients with consecutive and secondary (sensory) exotropia, and botulinum neurotoxin A (BTXA) is a recognized alternative to surgery in this group. PATIENTS AND METHODS: We revi...

Author: B Guyer

Abstract: Botulinum toxin type A is an important therapeutic agent for the treatment of movement and other disorders. As the clinical uses of botulinum toxin type A expand, it is increasingly important to understand the biochemical and pharmacological actions ...

Author: R Bhidayasiri

Abstract: Spasmodic dysphonia (SD) is a focal dystonia characterized by a strained, strangled voice. Botulinum toxin is a symptomatic treatment for SD and has become the mainstay of therapy over the last two decades. In this manuscript, we briefly review diffe...

Author: W Rosenthal

Abstract: We attempted to characterize ADP-ribose-amino acid bonds formed by various bacterial toxins. The ADP-ribose-arginine bond formed by botulinum C2 toxin in actin was cleaved with a half-life of about 2 h by treatment with hydroxylamine (0.5 M). In cont...

Author: Frank J Erbguth

Abstract: Food-borne botulism probably has accompanied mankind since its beginning. However, we have only few historical sources and documents on food poisoning before the 19th century. Some ancient dietary laws and taboos may reflect some knowledge about the ...

Author: Hans Bigalke

Abstract: In some patients, therapy with botulinum toxin type A (BT-A) becomes ineffective due to formation of antibodies (BT-A-AB). The time course of BT-A-AB titres after cessation of BT-A therapy was quantitatively studied to determine whether and when they...

Author: D D Truong

Abstract: Amongst all regions of the body, the craniocervical region is the one most frequently affected by dystonia. Whilst blepharospasm--involuntary bilateral eye closure--is produced by spasmodic contractions of the orbicularis oculi muscles, oromandibular...

Author: I Lindsey

Abstract: PURPOSE: This study was designed to assess whether addition of glyceryl trinitrate to botulinum toxin improves the healing rate of glyceryl trinitrate-resistant fissures over that achieved with botulinum toxin alone. METHODS: Patients were randomized...

Author: A Friedman

Abstract: During the last 5 years, 75 patients with focal dystonias were longitudinally treated with injections of botulinum toxin A. Each patient received 2-6 injections. The improvement was assessed after each injection and estimated as significant after 68....

Author: S Fahn

Abstract: Botulinum toxin type A (btx A) injections are the most effective treatment for most patients with focal dystonia. Some patients who improve after btx A injections and later lose response have serologic evidence of antibodies to btx A with the mouse n...

Author: Andrew John Lees

Abstract: We studied 20 patients with cervical dystonia who had started to respond poorly to botulinum toxin A (BTXA) injections after an initial good response. All patients had extensor digitorum brevis (EDB) tests performed in addition to BTXA immunoprecipit...

Author: H Schulte-Baukloh

Abstract: Botulinum toxin A has still not been approved for urologic indications leading to uncertainty of the user or those who would like to use it. Recently, a report of a European consensus panel on this topic was published in European Urology: Apostolidis...

Author: David Caird

Abstract: Discussion regarding botulinum toxin, immunologic considerations with long-term repeated use, with emphasis on cosmetic applications.

Author: R Ferrante

Abstract: Histochemical effects of botulinum B toxin were studied on fibers from longissimus dorsi muscle in Albino rabbits and compared to effects produced by botulinum A toxin. Acetylcholinesterase staining, muscle fiber size analysis, and ATPase staining in...

Author: G Comes

Abstract: PURPOSE: This randomized controlled trial was performed to compare the novel botulinum toxin type A free of complexing proteins (NT 201) with the marketed preparation BOTOX degrees regarding efficacy and tolerability. METHODS: Fourteen healthy volunt...

Author: I Ia Anosov

Abstract: After the per os administration of 1Dlm/ml of botulin, type B. there were observed at the period of development of the limb paralysis and myasthenia morphological changes in the locus coeruleus cells expressed in the development of a more pronounced ...