Population analyses of susceptibility to cefotaxime (CTX) and desacetyl-cefotaxime (DCTX) of strains of Staphylococcus and some genera of Enterobacteriaceae were carried out. DCTX, which is the main m...
We have prospectively studied 13 episodes of spontaneous bacterial peritonitis (SBP) in 12 patients treated with cefotaxime (CTX) 2 g intravenously every 8 h (mean duration, 5.3 days). Ascitic fluid w...
The activity of cefotaxime (CTX), desacetylcefotaxime (dCTX) and their combinations (CTX and dCTX in a 1:1 ratio) was tested against a variety of aerobic and anaerobic bacteria collected from clinical...
Serum levels of cefotaxime and desacetyl-cefotaxime were studied in 18 patients with hepatic cirrhosis after an intravenous bolus injection of 2 g of cefotaxime. Blood levels were independent of the d...
The pharmacokinetics of cefotaxime, a new semi-synthetic cephalosporin for injection, was studied in 30 subjects with various degrees of renal function after a single 1-gram intramuscular injection. S...