2D fragment-based similarity searching is one of the most popular techniques for searching a large database of chemical structures and has been widely applied in drug discovery. However, its performan...
The presentation of images that are similar to that of an unknown lesion seen on a mammogram may be helpful for radiologists to correctly diagnose that lesion. For similar images to be useful, they mu...
Abstract
Protein domains typically correspond to major functional sites of a protein. Therefore, determining similarity between domains can aid in the comparison of protein functions, and can provide...
A hardness based similarity index for studying the quantum similarity for atoms is analyzed. The investigation of hardness and Fukui functions of atoms leads to the construction of a quantum similarit...
Abstract
Based on similarity science and extension logic, this paper presents further exploration on a novel reasoning called similarity reasoning for solving incompatible problems. The reasoning is ...
Many questions in personality psychology lend themselves to the analysis of profile similarity. A profile approach to issues such as personality judgment, personality similarity, behavioral consistenc...
In this study we evaluate how far the scope of similarity searching can be extended to identify not only ligands binding to the same target as the reference ligand(s) but also ligands of other homolog...
MOTIVATION: As an increasing number of protein structures become available, the need for algorithms that can quantify the similarity between protein structures increases as well. Thus, the comparison ...