In the Drosophila CNS, early neuroblast formation and fate are controlled by the pair-rule class of segmentation genes. The distantly related Schistocerca (grasshopper) embryo has a similar arrangemen...
huckebein encodes a predicted zinc finger transcription factor which is transiently expressed in a subset of Drosophila central nervous system precursors (neuroblasts (NBs)). We used DiI cell lineage ...
Individual neural progenitors generate different cell types in a reproducible order in the retina, cerebral cortex and probably in the spinal cord. It is unknown how neural progenitors change over tim...
Although spatial patterning during embryonic development is well characterized, a corresponding framework for temporal patterning has not been established. In this issue, Zhu et al. (2006) identify th...
The Drosophila central nervous system (CNS) develops from a heterogeneous population of neural stem cells (neuroblasts), yet the genes regulating neuroblast determination remain unknown. The segmentat...
INTRODUCTION: Disturbances of neuroblast migration are prominent among the numerous causes of symptomatic epilepsy and of abnormal neurological development in children. DEVELOPMENT: Although their cli...