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- Getting more and more complex: the pathophysiology of atopic eczema.
- Atopic eczema (AE) is a multifactorial chronic inflammatory skin disease characterized by pruritic, typically distributed eczematous skin lesions. Deficiencies in innate and adaptive immunity based on...
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Uploaded: 2007-6-2
- Fc receptors as determinants of allergic reactions.
- Activation of the high-affinity receptor for IgE (FcepsilonRI) on allergic effector cells induces a multitude of positive signals via immunoreceptor tyrosine-based activation motifs, which leads to th...
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Uploaded: 2005-12-6
- Pathogenesis of atopic dermatitis: new developments.
- Atopic dermatitis (AD) is a paradigmatic skin disease in which multiple gene-gene and gene-environment interactions play a pivotal role. Although the complex pathophysiologic network of AD explains th...
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Uploaded: 2009-10-10
- DRESS syndrome associated with carbamazepine and phenytoin.
- Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome reflects a serious hypersensitivity reaction to drugs. Its clinical manifestations include diffuse maculopapular rash, exfoliative de...
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Uploaded: 2004-9-11
- Genetic aspects of melatonin biology.
- For decades, the important physiological roles of the pineal hormone have inspired scientific investigations. Research efforts have generated a broad amount of information relevant to various genetic ...
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Uploaded: 2004-9-11
- Dendritic cells in allergen-specific immunotherapy.
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Uploaded: 2009-6-6
- Pathogenesis, diagnosis, and treatment of aspirin intolerance.
- OBJECTIVES: To provide an overview of aspirin intolerance (AI), to summarize the latest genetic and pathophysiologic findings, and to discuss the current therapeutic recommendations, including aspirin...
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Uploaded: 2007-7-27
- Allergen specific immunotherapy for atopic dermatitis.
- PURPOSE OF REVIEW: To describe recent developments as well as the pros and cons of allergen specific immunotherapy as a putative therapeutic option for a subgroup of patients with atopic dermatitis. R...
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Uploaded: 2007-11-9