Results for:
"
Meindert+Hobbema
" in Documents
- Nausea caused by a jejunal lipoma.
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Uploaded: 2009-3-10
- Animal-to-human extrapolation of the pharmacokinetic and pharmacodynam...
- OBJECTIVES: This investigation describes the interspecies scaling of the pharmacokinetics and pharmacodynamics of buprenorphine. METHODS: Data on the time course of the antinociceptive and respiratory...
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Uploaded: 2007-5-1
- The missing link between clinical endpoints and drug targets in depres...
- Identification of the neurochemical processes associated with mood disorders has led to the selection of novel targets for the treatment of depression. Drug screening is consequently performed under t...
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Uploaded: 2010-2-2
- Pharmacodynamic analysis of the anticonvulsant effects of tiagabine an...
- PURPOSE: The pharmacodynamic interaction between the antiepileptic drugs (AEDs) tiagabine (TGB) and lamotrigine (LTG) was characterized on basis of the anticonvulsant effect in the cortical stimulatio...
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Uploaded: 2004-4-23
- Synergistic combinations of anticonvulsant agents: what is the evidenc...
- PURPOSE: Combination therapy is often used in the treatment of seizures refractory to monotherapy. At the same time, the pharmacodynamic mechanisms that determine the combined efficacy of antiepilepti...
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Uploaded: 2007-3-10
- Pharmacokinetic-pharmacodynamic model for the reversal of neuromuscula...
- BACKGROUND: Sugammadex selectively binds steroidal neuromuscular blocking drugs, leading to reversal of neuromuscular blockade. The authors developed a pharmacokinetic-pharmacodynamic model for revers...
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Uploaded: 2009-1-23
- Extensions to the visual predictive check to facilitate model performa...
- The Visual Predictive Check (VPC) is a valuable and supportive instrument for evaluating model performance. However in its most commonly applied form, the method largely depends on a subjective compar...
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Uploaded: 2008-1-17
- Pharmacokinetic-pharmacodynamic modeling of the effect of fluvoxamine ...
- The pharmacokinetic-pharmacodynamic (PK-PD) correlation of the effect of fluvoxamine on para-chloroamphetamine (PCA)-induced behavior was determined in the rat. Rats (n=66) with permanent arterial and...
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Uploaded: 2007-9-11