Ecdysone metabolism was investigated in the white mouse Mus musculus. It was shown to involve dehydroxylation at C-14, followed by reduction of ring B into a 6 alpha-hydroxy derivative and epimerizati...
The herbicide, Kerb ((N-(1,1 dimethylpropynyl)-3,5-dichlorobezamide) was fed to a lactating cow at a concentration of 5 ppm in the ration for four days. Excretion of residues of equivalent herbicide i...
Drug transporters are increasingly recognized as a key determinant of drug disposition and response. It is now widely appreciated that expression of the ATP-dependent efflux transporter, MDR1 (ABCB1, ...