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Kaiso
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- Nuclear import of the BTB/POZ transcriptional regulator Kaiso.
- Kaiso is a BTB/POZ transcription factor that functions in vitro as a transcriptional repressor of the matrix metalloproteinase gene matrilysin and the non-canonical Wnt signaling gene Wnt-11, and as a...
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Uploaded: 2004-11-27
- A role for Kaiso-p120ctn complexes in cancer?
- Kaiso belongs to the zinc finger and broad-complex, tramtrack and bric-a-brac/poxvirus and zinc finger (BTB/POZ) protein family that has been implicated in tumorigenesis. Kaiso was first discovered in...
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Uploaded: 2005-11-19
- Regulation of the rapsyn promoter by kaiso and delta-catenin.
- Rapsyn is a synapse-specific protein that is required for clustering acetylcholine receptors at the neuromuscular junction. Analysis of the rapsyn promoter revealed a consensus site for the transcript...
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Uploaded: 2004-7-30
- Kaiso is a bimodal modulator for Wnt/beta-catenin signaling.
- The Wnt family of secreted ligands plays critical roles during embryonic development and tumorigenesis. Here we show that Kaiso, a dual specific DNA-binding protein, functions as a bimodal regulator o...
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Uploaded: 2009-3-21
- KAISO--a new member of the BTB/POZ family specifically bindsto methyl...
- A protein specifically binding a symmetrically methylated DNA fragment of the first intron of the mts1 gene was studied. The protein was purified by gel filtration and affinity chromatography. Mass sp...
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Uploaded: 2001-8-24
- Dancing in and out of the nucleus: p120(ctn) and the transcription fac...
- The catenin p120 (hereafter p120(ctn)) was first identified as a Src kinase substrate and subsequently characterized as an Armadillo catenin member of the cell-cell adhesion cadherin-catenin complex. ...
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Uploaded: 2006-10-20
- Kaiso-deficient mice show resistance to intestinal cancer.
- Kaiso is a BTB domain protein that associates with the signaling molecule p120-catenin and binds to the methylated sequence mCGmCG or the nonmethylated sequence CTGCNA to modulate transcription. In Xe...
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Uploaded: 2005-12-16
- Methylation specific binding activity of zinc finger protein Kaiso
- OBJECTIVE: To compare binding activity of different zinc finger domain of human Kaiso with methylated CpG. METHODS: pGEX constructs with different human Kaiso domain were generated and then correspond...
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Uploaded: 2007-10-25