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- Increased expression of the PRAD-1/CCND1 gene in hairy cell leukaemia.
- The PRAD-1/CCND1 gene encodes Cyclin D1, a cyclin involved in cell cycle regulation at the G1-S transition. Over-expression of this gene is a highly specific molecular marker of mantle cell lymphomas ...
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Uploaded: 1995-12-1
- The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subs...
- The PRAD-1/cyclin D1 proto-oncogene is localized on chromosome 11q13 and it is overexpressed in several tumour types as a consequence of gene amplification or chromosomal rearrangements. In this study...
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Uploaded: 1994-8-15
- Rearrangement and overexpression of the BCL-1/PRAD-1 gene in intermedi...
- The t(11;14)(q13;q32) translocation and its molecular counterpart, BCL-1 rearrangement, are consistent features of intermediate lymphocytic lymphoma (ILL). Rearrangement is thought to deregulate the n...
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Uploaded: 1993-6-1
- PRAD-1 (CCND1)/cyclin D1 oncogene amplification in primary head and ne...
- BACKGROUND. Abnormalities in chromosome 11q13 regions have been frequently found in head and neck squamous carcinoma. Recent studies indicate that the PRAD-1 (also CCND1), which encodes cyclin D1, is ...
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Uploaded: 1994-7-1
- Unexpected Prad-1 amplification in multiple simultaneous localisations...
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Uploaded: 1993-1-1
- PRAD-1/cyclin D1 gene amplification correlates with messenger RNA over...
- PRAD-1 is a putative oncogene localized on chromosome 11q13 which encodes cyclin D1, a novel cyclin involved in cell cycle regulation. Amplification of this gene has recently been reported in several ...
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Uploaded: 1994-9-1
- Altered p16/MTS1/CDKN2 and cyclin D1/PRAD-1 gene expression is associa...
- The p16/MTS1/CDKN2 gene and the cyclin D1/PRAD-1 gene cooperatively regulate cyclin-dependent kinase 4-mediated phosphorylation of pRB in the cell cycle of normal cells. p16/CDKN2 gene and cyclin D1/P...
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Uploaded: 1998-11-17
- PRAD-1/cyclin D1 gene overexpression in chronic lymphoproliferative di...
- The t(11;14)(q13;q32) translocation and its molecular counterpart bcl-1 rearrangement are frequently associated with mantle cell lymphomas (MCLs) and only occasionally with other variants of B-cell ly...
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Uploaded: 1994-10-15