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- Orthogonal protein purification--expanding the repertoire of GST fusio...
- We have previously developed a labeling scheme that can be used to site-specifically link human glutathione transferases (hGSTs) from the alpha class to chemical entities such as fluorophores and alde...
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Uploaded: 2007-10-30
- Spectroscopic characterization of a molecule with a weak bond: the BrO...
- Pure rotational spectra of the BrOO radical for the 79Br and 81Br isotopomers have been observed using a Fourier transform microwave spectrometer. The radical was produced in a supersonic jet by disch...
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Uploaded: 2005-7-30
- A promiscuous glutathione transferase transformed into a selective thi...
- Human glutathione transferase A1-1 (hGST A1-1) can be reengineered by rational design into a catalyst for thiolester hydrolysis with a catalytic proficiency of 1.4 x 10(7) M(-1). The thiolester hydrol...
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Uploaded: 2005-12-17
- Combinatorial chemical reengineering of the alpha class glutathione tr...
- Previously, we discovered that human glutathione transferases (hGSTs) from the alpha class can be rapidly and quantitatively modified on a single tyrosine residue (Y9) using thioesters of glutathione ...
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Uploaded: 2004-7-22
- Programmed delivery of novel functional groups to the alpha class glut...
- Here we describe a new route to site- and class-specific protein modification that will allow us to create novel functional proteins with artificial chemical groups. Glutathione transferases from the ...
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Uploaded: 2003-8-27
- Induction of structure and function in a designed peptide upon adsorpt...
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Uploaded: 2006-11-24
- Ligand-directed labeling of a single lysine residue in hGST A1-1 mutan...
- Previously, we discovered that human glutathione transferase (hGST) A1-1 could be site-specifically acylated on a tyrosine residue (Y9) to form ester products using thiolesters of glutathione (GS-thio...
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Uploaded: 2005-7-21
- A Multipurpose receptor composed of promiscuous proteins. Analyte dete...
- A multipurpose receptor akin to the "electronic nose" was composed of coumarin-labeled mutants of human glutathione transferase A1. We have previously constructed a kit for site-specific modification ...
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Uploaded: 2007-10-18