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Homology+%28biology%29%22
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- Activation of the Abl tyrosine kinase in vivo by Src homology 3 domain...
- The nonreceptor tyrosine kinase c-Abl is tightly regulated in vivo, but the mechanisms that normally repress its activity are not well understood. We find that a construct encoding the first two Src h...
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Uploaded: 1999-9-17
- Duet is a novel serine/threonine kinase with Dbl-Homology (DH) and Ple...
- We show here the identification of Duet, a novel molecule bearing serine/threonine kinase, Dbl-Homology (DH), and Pleckstrin-Homology (PH) domains. The kinase domain of Duet shows a homology to that o...
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Uploaded: 1999-2-19
- Homology Stratifications and Intersection Homology
- A homology stratification is a filtered space with local homology groups constant on strata. Despite being used by Goresky and MacPherson [3] in their proof of topological invariance of intersection h...
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Uploaded: 13-05-09
- Structural homology of lens crystallins. II. Homology expressed by cor...
- Bovine lens alpha A- and alpha B-crystallin polypeptides show extensive sequence homology with each other, but apparently none with beta Bp- and gamma 2-crystallin. Despite only 30% sequence homology,...
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Uploaded: 1983-10-17
- Homology and homocracy revisited: gene expression patterns and hypothe...
- Homocracy, a term referring to shared regulatory gene expression patterns between organs in different animals, was introduced recently in order to prevent inappropriate inference of organ homology bas...
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Uploaded: 2004-6-29
- Repair of DNA interstrand cross-links: interactions between homology-d...
- DNA interstrand cross-links (ICLs) are complex DNA lesions generated by bifunctional alkylating agents, a class of compounds extensively used in cancer chemotherapy. Formation of an ICL covalently lin...
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Uploaded: 2006-3-30
- Control of intramolecular interactions between the pleckstrin homology...
- Vav and Sos1 are Dbl family guanine nucleotide exchange factors, which activate Rho family GTPases in response to phosphatidylinositol 3-kinase products. A pleckstrin homology domain adjacent to the c...
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Uploaded: 2000-4-5
- Using multiple templates to improve quality of homology models in auto...
- When researchers build high-quality models of protein structure from sequence homology, it is today common to use several alternative target-template alignments. Several methods can, at least in theor...
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Uploaded: 2008-4-29