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- An Arg/Ser substitution in the second epidermal growth factor-like mod...
- Factor IXR94S is a naturally occurring hemophilia B defect, which results from an Arg 94 to Ser mutation in the second epidermal growth factor (EGF)-like module of factor IX. Recombinant factor IXR94S...
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Uploaded: 1999-6-25
- First epidermal growth factor-like domain of human blood coagulation f...
- Factor IX consists of a gamma-carboxyglutamic acid-rich domain followed by two epidermal growth factor (EGF)-like domains and the C-terminal protease domain. To delineate the function of EGF1 domain i...
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Uploaded: 1994-4-26
- Factor IX variants of hemophilia B. The effect of activated factor XI ...
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Uploaded: 1979-1-1
- Purification and properties of an abnormal blood coagulation factor IX...
- An abnormal blood coagulation factor IX has been isolated from the blood of a hemophilia B patient with a variant of the disease (hemophilia Bm) characterized by a normal concentration of factor IX an...
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Uploaded: 1981-2-23
- Pathogenic antibodies to coagulation factors. Part II. Fibrinogen, pro...
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Uploaded: 2005-6-28
- The first epidermal growth factor-like domains of factor Xa and factor...
- During tissue factor (TF)-induced coagulation, the factor (F)VIIa-TF complex activates factor (F)X and factor (F)IX. Through positive feedback, the generated FXa and FIXa activate FVII-TF. The first e...
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Uploaded: 2005-1-7
- Heterogeneity of factor IX BM. Difference of cleavage sites by factor ...
- Abnormal factor IX was isolated from the plasma of a patient with hemophilia B Kashihara and two patients with hemophilia BM. The F.IX was purified to homogeneity by using monoclonal anti-F.IX-Sephros...
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Uploaded: 1986-6-1
- Probing the interface between factor Xa and tissue factor in the quate...
- Blood coagulation is triggered by the formation of a complex between factor VIIa (FVIIa) and its cofactor, tissue factor (TF). TF-FVIIa is inhibited by tissue factor pathway inhibitor (TFPI) in two st...
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Uploaded: 2003-6-6