G protein-coupled receptors (GPCRs) and their signal transductions are important for both physiological and pathological processes in neuron systems. Neuronal GPCRs activated by synthetic ligands have...
The M4 muscarinic acetylcholine (ACh) receptor (mAChR) is a potential therapeutic target but characterized by a lack of subtype-selective ligands. We recently generated "designer receptors exclusively...
This review focuses on the development of acid catalysis for selective organic transformations conducted in our laboratories for the past 30 years. Several important concepts in designing of catalysts...
Notice of Copyright Inform, the program and its source code, its example games and documentation, including the text and typography of this book, are copyright c ? Graham Nelson 1993,
Naturally existing biological systems, from the simplest unicellular diatom to the most sophisticated organ such as the human brain, are functional self-assembled architectures. Scientists have long b...