Benzodiazepines are widely used anxiolytic and anticonvulsant drugs, and brain receptors for these drugs have been characterized by Möhler and Okada and Squires and Braestrup. Recently, substances th...
Anxiogenic effects of m-CPP in patients with panic disorder: comparison to caffeine's anxiogenic effects.
Klein E, Zohar J, Geraci MF, Murphy DL, Uhde TW.
Section of Anxiety and Affective Disorders,...
The behavioral and neuroendocrine effects of meta-chlorophenylpiperazine (m-CPP), a serotonergic agonist, were compared with the effects of caffeine, an adenosine antagonist, in panic disorder patient...
Previous work in male Swiss Webster (CFW) mice demonstrated a long lasting effect of predator stress on risk assessment in the elevated plus maze (EPM). Most severe effects (increases in risk assessme...
The contrast of attitudes to the psychiatric effects of caffeine between North America and Britain is highlighted. A summary of the dietary sources, pharmacology and effects on caffeine on normal subj...
Rats were trained to discriminate an injection of pentylenetetrazol (PTZ), 20 mg/kg, from saline using a two-lever operant procedure with food as a reinforcer. In substitution tests, rats selected the...