Lymphotropic nanoparticle enhanced MRI for the staging of genitourinary tumors

Current imaging modalities lack sufficient sensitivity and specificity for the noninvasive staging of lymph nodes in genitourinary cancers. In this Review, Mouli and colleagues from Northwestern University discuss the potential role of lymphotropic nanoparticles—which selectively accumulate in benign lymph nodes—in enhancing the MRI detection of nodal metastases.