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Bacteria-Killing Nanofactories - Bioengineering May Defeat Antibiotic-Resistant Germs

(TrendHunter.com) Engineered biological nanofactories may be able to prevent bacterial infections by confusing bacteria and stop them from spreading, without the use of antibiotics. Research from the A. James Clark School…

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  • Katrine Mellersh, Durham

    Lots of chemicals kill bacteria (bacteriocidal compounds), or slow down their replication (bacteriostatic compounds), for example bleach or cyanide. The trick is finding those that don’t do the same to humans. These ‘antibiotics’ can work in many ways: they simply need to disrupt something specific to bacterial biochemistry.

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  • Researchers uncover nitrogen-fixing bacteria in the ants' gardens [Read more]

  • Cigarettes are massive germ factories that may expose users and passersby to a swarm of disease-causing bacteria, a study shows.

  • Variation in our microbial inhabitants could help tailor efforts to treat illness. via Technology Review: You Are Your Bacteria.

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  • Research presented today sheds new light on the role bacteria in the digestive tract may play in obesity. The studies, which were presented at the 110th General Meeting of the American Society for Microbiology, paint a picture that may be more complex than originally thought.
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  • The bacteria responsible for most cases of food poisoning in the U.S. has been turned into an efficient biological factory to make chemicals , medicines and, now, fuels. Chemical engineer Jay Keasling of the University of California, Berkeley, and his colleagues have manipulated the genetic code of Escherichia coli , a common gut bacteria, so that it can chew up plant-derived sugar to produce diesel and other hydrocarbons, according to results published in the January 28 issue of Nature .

  • (American Society for Microbiology) Research presented today sheds new light on the role bacteria in the digestive tract may play in obesity. The studies, which were presented at the 110th General Meeting of the American Society for Microbiology, paint a picture that may be more complex than originally thought.

  • Once you’ve made the decision to encase a few men in a metal pod and shoot the vessel into space, what you don’t want is to have something they eat make them sick. Astronauts in space already have suppressed immune systems, and the added complications of food poisoning and its attendant symptoms—dehydration, diarrhea—when both water and privacy are limited likely goes without saying. That’s why, in the late 1950s, just as NASA was embarking on the era of manned space flight, the agency went to its food supplier, Pillsbury, with a request: ensure that the food we’re feeding astronauts won’t have enough bacteria and other contaminants to make our astronauts sick. Pillsbury came through, crafting a science-based system that, for the first time, examined step-by-step how food was made, rather than the final product, with a focus on the riskiest ingredients and processes. By 1959, the problem of food-sickened astronauts was effectively kicked.

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  • It seems like pee, or more specifically urea, is becoming quite the sustainable ingredient.  Beyond being tapped as a good source of hydrogen, it's powering batteries and is now being used to make sustainable bricks.

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  • Because genetically monomorphic bacterial pathogens harbour little DNA sequence diversity, most current genotyping techniques used to study the epidemiology of these organisms are based on mobile or repetitive genetic elements. Molecular markers commonly used in these bacteria include Clustered Regulatory Short Palindromic Repeats (CRISPR) and Variable Number Tandem Repeats (VNTR). These methods are also increasingly being applied to phylogenetic and population genetic studies. Using the Mycobacterium tuberculosis complex (MTBC) as a model, we evaluated the phylogenetic accuracy of CRISPR- and VNTR-based genotyping, which in MTBC are known as spoligotyping and Mycobacterial Interspersed Repetitive Units (MIRU)-VNTR-typing, respectively.

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  • Viruses of soil bacteria (phages) evolve to improve their ability to infect the bacterial hosts that surround them. This is shown in a new study. Phages appear to be better able to infect bacteria from the same small soil sample than bacteria from just a few centimeters away. Evolution can therefore restructure ecosystems on a very small scale.