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Amyloid beta 42 peptide (A{beta}42)-lowering compounds directly bind to A{beta} and interfere with amyloid precursor protein (APP) transmembrane dimerization [Biochemistry]
Mon, 2010-08-02 20:52 — Anonymous
Following ectodomain shedding by β-secretase, successive proteolytic cleavages within the transmembrane sequence (TMS) of the amyloid precursor protein (APP) catalyzed...
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