A new method for creating nanofibers made of proteins promises to greatly improve drug delivery methods, aid in regenerating human tissue, and pave the way to an organic method of building nanofibers for tiny, powerful microprocessors. Researchers have discovered how to make nanofibers using the COMP protein found in human cartilage.
(The Yates Network) BIND Biosciences published preclinical and clinical data in Science Translational Medicine showing promising effects in solid tumors and successful clinical translation of BIND-014, the first targeted and programmed nanomedicine to enter human clinical studies.
(Brigham and Women's Hospital) A team of scientists have found promising effects of a first-in-class targeted cancer drug called BIND-014 in treating solid tumors.
Senior chimpanzees appear to show the young 'uns how to recognise plants with medicinal properties – but the finding is controversial
Anecdotes are not data, the saying goes, but people sure believe them. An article in JAMA says doctors should consider the use of narrative, patient stories and testimonials, to boost public acceptance of health issues such as cancer screenings and vaccination mandates.
Nature Reviews Drug Discovery10, 835–852 (2011)| 10.1038/nrd3578The following sentence was inadvertently duplicated on page 835: Subsequently, several other nanomedicinal therapeutics have been approved for clinical use, including an albumin-bound nanoparticle delivering paclitaxel for the treatment of breast
Emerging insights into the basic biology of cancer have led to the development of novel, tailored treatments for patients based on existing specific genetic profiles and other biomarkers. Several of these, such as Herceptin and Gleevec, have shown considerable commercial success, with worldwide sales of
A Loose End
In the last post I wondered if Ted Kaptchuk, when he wrote the article titled “Effect of interpretive bias on clinical research,” had understood this implication of Bayes’s Theo
And the Lord spake, saying, “First shalt thou take out the Holy Pin. Then shalt thou count to three, no more, no less. Three shall be the number thou shalt count, and the number of the counting shall be three. Four shalt thou not count, neither count thou two, excepting that thou then proceed to three. Five is right out.
It's been a mere two days since Steve Jobs died. Although it hasn't yet been revealed what his specific cause of death was, it's a good bet that Jobs' death was due to a recurrence of his pancreatic cancer, first diagnosed in 2003, for which he underwent surgery in 2004 and ultimately a liver transplant in 2009.