Group - Serotonin transporter

 

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Prozac Selective Serotonin Reuptake Inhibitor SSRI

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  • ® blocks the reuptake of serotonin by disabling the transporter proteins. Con...




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The serotonin transporter (SERT) is a monoamine transporter protein. This protein is an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamine, cocaine, and MDMA, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma. It reuptakes serotonin in the synaptic cleft and terminates its function. It allows neurons, platelets, and other cells to accumulate the chemical neurotransmitter serotonin, which affects emotions and drives. 



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        • When It Comes To Depression, Serotonin Isn't The Whole Story
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          Traditional antidepressants like Prozac are widely used to treat depression by boosting serotonin levels, which researchers have long believed are at the root of depression. Research shows that other drugs, including ketamine — also known by its street name, Special K — may be more effective.
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          A groundbreaking study published in Elsevier's Epilepsy & Behavior provides evidence in mouse model that drugs known as Selective Serotonin Reuptake Inhibitors (SSRIs; one category of antidepressants) may reduce the risk of Sudden Unexpected Death in Epilepsy (SUDEP).
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          Prescription pills are pictured in a file photo. Widely used antidepressants known as selective serotonin reuptake inhibitors (SSRIs) may delay a woman's breast milk production soon after giving birth, a new study hints.
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          A groundbreaking study published in Elsevier's Epilepsy & Behavior provides evidence in mouse model that drugs known as Selective Serotonin Reuptake Inhibitors (SSRIs; one category of antidepressants) may reduce the risk of Sudden Unexpected Death in Epilepsy (SUDEP).
        • Antidepressants Are Associated With Increased Risk of Falling
          Nursing home residents with dementia who use average doses of selective serotonin reuptake inhibitors (SSRIs) are three times more likely to have an injurious fall than similar people who don’t use these drugs. The association can be seen in people who use low doses of SSRIs and the risk increases as people take higher doses. The results are published in the British Journal of Clinical ...
        • Nursing home residents with dementia: Antidepressants are associated with increased risk of falling
          Nursing home residents with dementia who use average doses of selective serotonin reuptake inhibitors (SSRIs) are three times more likely to have an injurious fall than similar people who don't use these drugs. The association can be seen in people who use low doses of SSRIs and the risk increases as people take higher doses. The results are published in the British Journal of Clinical ...
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