Group - Dr. Brain

'PROTECT'ing the Brain: Emory University doctors are studying the use of progest...

The entire neural network of a mouse's brain has been seen in 3D for the first t...

Scientists have discovered that a large expanse of a musician's brain "shuts off...

This is a brief cut from a one hour lecture about ADD/ADHD. In this clip Craig i...

Scientists are finding that it truly is the brain that decides what is or isn't ...

Very sorry about the poor sound quality References: Schlaepfer et al (2008) Deep...

Dr. Arthur Kellermann, chairman of Emory's Department of Emergency Medicine and ...

Segment from Science Channel interviewing Larry Farwell about brain fingerprinti...

Read more at www.newscientist.com Have you ever experienced that eerie feeling o...

Episode 11: The Persistence of Memory Contents: 1. Opening Bits, the basic units...

Walter Russell Brain, 1st Baron Brain (October 23 1895 – December 29 1966) was a British neurologist. He was principal author of the standard work of neurology, Brain's Diseases of the Nervous System, and longtime editor of the neurological medical journal titled Brain.

Train Your Brain: 60 Days to a Better Brain is an English language version of a Japanese book written by Ryuta Kawashima. The original book sold over a million copies in Japan.

Dr. Brain is a series of educational games made by Sierra On-Line in the 1990s.

The Brain That Changes Itself: Stories of Personal Triumph from the frontiers of brain science is a book on neuroplasticity by psychiatrist and psychoanalyst Norman Doidge, M.D.

Brain is a medical thriller written by Robin Cook. It describes how a future generation of computers will work hard-wired to human brains.

"If I Only Had a Brain" (also "If I Only Had a Heart" and "If I Only Had the Nerve") is a song in the 1939 film The Wizard of Oz by Harold Arlen (music) and E.Y. Harburg (lyrics). The song is sung by the characters that meet Dorothy talking about what each character wants from the Wizard. The Scarecrow's version of the song is sung about getting a brain. The original recording included an extravagant Busby Berkley-choreographed dance routine, but this was eventually cut for length reasons. A closing vocal stanza was likewise cut.

Abstract: It has been suggested, from studies of a rabbit model of fulminant hepatic failure, that hepatic encephalopathy might be related to an increase in brain gamma-aminobutyric acid uptake through a more permeable bloodbrain barrier, leading to an overactivity of brain gamma-aminobutyric acid-mediated inhibitory neurotransmission. Five groups of dogs were studied: normal dogs, dogs with secondary biliary cirrhosis without and with hepatic encephalopathy and portacaval shunted dogs without and with hepatic encephalopathy. Brain gamma-aminobutyric acid and sucrose uptake was investigated using the mu...

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Abstract: Traditional beliefs about two aspects of glucose regulation in the brain have been challenged by recent findings. First, the absolute level of glucose in the brain's extracellular fluid appears to be lower than previously thought. Second, the level of glucose in brain extracellular fluid is less stable than previously believed. In vivo brain microdialysis was used, according to the method of zero net flux, to determine the basal concentration of glucose in the extracellular fluid of the striatum in awake, freely moving rats for comparison with recent hippocampal measurements. In addition, extr...

Abstract: The synthesis of ceramide from lignoceric acid was studied in normally developing rat brain and jimpy mouse brain. The developmental pattern of the synthesis of both non-hydroxy and hydroxyceramide from free lignoceric acid in a brain-specific pathway requiring NADPH and cytosolic factors was similar to the synthesis from lignoceroyl CoA and both showed increasing activity during myelination. There were no differences in non-hydroxyceramide synthesis between jimpy and normal littermate control mouse brains by both pathways. HPLC analysis showed the same non-hydroxyceramide level in both types ...

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Abstract: While continuous monitoring of brain tissue oxygenation (P(ti)O2) is known as a practicable, safe and reliable monitoring technology supplementing traditional ICP-CPP-monitoring, the impact of cerebral microdialysis, now available bedside, is not proven extensively. Therefore our studies focused on the practicability, complications and clinical impact of microdialysis during long term monitoring after acute brain injury, especially the analysis of the correlation between changes of local brain oxygenation and metabolism. Advanced neuromonitoring including ICP-CPP-p(ti)O2 was performed in 20 pa...

Abstract: Experimental tumors and abscesses were produced by intrahemispheric inoculation of a blastomatous glial cell clone and of staphylococcus aureus, respectively. In both models severe vasogenic brain edema developed. The site of the barrier lesion was identified by systemic application of Evans blue or peroxidase, and the spread of edema by immunoautoradiographic localisation of extravasated serum proteins. In both experimental conditions, serum proteins accumulated diffusely in the white matter of the ipsilateral hemisphere, although the barrier lesion was strictly confined to the pathological f...

Abstract: The blood-brain relationship for stearic acid varies during development. Subcutaneously injected [1-14C]-stearic acid is taken up by brain. Age-related changes in the metabolism of stearic acid have been determined in mouse brain from birth to maturity. Total lipid radioactivity reaches a maximum at 18 days of age and decreases afterwards until adulthood. However, specific radioactivity presents the highest value at 1 day of age and declines from then on. At any age, the injected acid is taken up and partly metabolized in the brain, either by elongation or by degradation in situ and resynthesi...

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Abstract: OBJECTIVE: To support the hypothesis about the potential compensatory role of ipsilateral corticofugal pathways when the contralateral pathways are impaired by brain tumours. METHODS: Retrospective analysis was carried out on the results of functional MRI (fMRI) of a selected group of five paretic patients with Rolandic brain tumours who exhibited an abnormally high ipsilateral/contralateral ratio of activation-that is, movements of the paretic hand activated predominately the ipsilateral cortex. Brain activation was achieved with a flexion extension of the fingers. Statistical parametric acti...

Abstract: In the first part of the publication the authors presented the blood-brain (BBB) under physiological conditions. The second part includes the current opinions concerning BBB during various disorders of the central nervous system (CNS) and hypertension. The imbalance of BBB is often not only a consequence of a pathologic status, but can be also cause of it. On the other hand BBB influences the therapy of many illnesses by restricting the penetration of drugs to the CNS.

Abstract: In addition to the findings of neuroscientific research on brain function, reviewed in the previous articles (Meissner, 2006a, 2006b), contemporary findings relevant to the mind-brain relation derive also from the study of the underlying patterns of brain dysfunction related to various forms of psychopathology. Other information derives from study of split-brain conditions and from research on dream processes and their relation to brain mechanisms. Review of these research findings casts further light on aspects of the mind-brain relation and further substantiates a unified theory of mind-brai...

Abstract: BACKGROUND. The endothelial cell marker PAL-E is not reactive to vessels in the normal brain. The present study concerns the PAL-E reactivity in brain tumors in contrast to normal brain and nonneoplastic brain disease. METHODS. A total of 122 specimens were examined: brain tumors (n = 94), nonneoplastic brain disease (n = 19), normal brain (n = 8), and fetal brain (n = 1). Standard immunohistochemical procedures using a panel of endothelial cell markers were applied to detect vessels reactive to PAL-E. RESULTS. PAL-E reactivity to endothelial cells was found in all cases of glioblastoma multif...