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Group description
Thyroid hormone receptor beta (TR-beta) (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian), also known as NR1A2 (nuclear receptor subfamily 1, group A, member 2), is nuclear receptor protein encoded by the THRB gene. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Defects in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several transcript variants have been observed for this gene, but the full-length nature of only one has been observed so far.
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News
- Supermodel Karolina Kurkova: Thyroid Caused Early Menopause
Kurkova Says She Packed on 30 Pounds, Too - Screening Moms-to-Be for Thyroid Trouble May Not Help Offspring
WEDNESDAY, Feb. 8 (HealthDay News) -- Screening and treating expectant moms for thyroid problems at the end of the first trimester doesn't improve children's IQs at age 3, a new study finds. - Model: Thyroid Caused Menopause at 24
Supermodel Karolina Kurkova says thyroid problems three years ago caused a 30-pound weight gain and early menopause. - Thyroid cancer three times more common in women than men
While only 5 percent of thyroid nodules or lumps are cancerous and most people don't know they have them, there are some possible warning signs. - Antenatal thyroid screening fails to improve IQ in 3-year-olds
( Cardiff University ) Children of mothers screened and treated for reduced thyroid function during pregnancy show no signs of improved IQ compared to women who receive no treatment, new research has uncovered. - Thyroid function important during pregnancy
When Vanessa McHugh became pregnant with twins, the Guelph woman was relieved to get a specialist’s help to manage her thyroid hormone level. - Common scans could hurt thyroid, researchers say
NEW YORK (Reuters Health) - The iodide dye used in heart scans and other medical imaging might damage some people's thyroid glands, which could cause important health problems later on, researchers say. In a new study, they found patients who had signs of thyroid disease were between two and three times as likely to have had a scan using iodide as a comparison group of people without thyroid ... - Routine Scans May Cause Thyroid Problems
People who undergo common procedures, such as CT scans and angiograms, may be at greater risk for thyroid problems, according to a recent study. - The American Association of Clinical Endocrinologists Launches New Thyroid Awareness Ribbon and Website in Honor of ...
JACKSONVILLE, FL-- - January is Thyroid Awareness Month and the American Association of Clinical Endocrinologists is introducing a new awareness ribbon as the icon for Thyroid Awareness. Joining the ranks ... - Living with Vitality column: Feeling sluggish? Check your thyroid
The thyroid gland is a two-inch long gland in the neck that has an important job: producing the thyroid hormones that regulate the body's metabolic function (the body's use of energy). A sluggish thyroid, or hypothyroidi Copyright 2012 Vail Daily. All rights reserved. This material may not be published, broadcast, rewritten or redistributed. Vail Daily Living with Vitality column: Feeling ...