Capsule structure of Proteus mirabilis ATCC 49565


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  • Author:  Beynon LM  Dumanski AJ  McLean RJ  MacLean LL  Richards JC  Perry MB.  

  • Abstract:  Capsule structure of Proteus mirabilis (ATCC 49565). Beynon LM, Dumanski AJ, McLean RJ, MacLean LL, Richards JC, Perry MB. Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada. Proteus mirabilis 2573 (ATCC 49565) produces an acidic capsular polysaccharide which was shown from glycose analysis, carboxyl reduction, methylation, periodate oxidation, and the application of one dimensional and two-dimensional high-resolution nuclear magnetic resonance techniques to be a high-molecular-weigh t polymer of branched trisaccharide units composed of 2-acetamido-2-deoxy- D-glucose (N-acetyl-D-glucosam ine), 2-acetamido-2,6-dide oxy-L-galactose (N-acetyl-L-fucosami ne), and D-glucuronic acid, having the structure: [formula: see text] P. mirabilis 2573 also produces an O:6 serotype lipopolysaccharide in which the O-chain component has the same structure as the homologous capsular polysaccharide. This is the first report of a defined capsular polysaccharide in this bacterial genus. PMID: 1551839 [PubMed - indexed for MEDLINE] PMCID: PMC205835

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