Incidence of hepatitis C virus infection in burn patients detection of anti-C100 anti-C33c and anti-Core antibodies
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PubMed
(0) (0 Votes)Views: (1053) Date: (27-01-09) Pages: () -
Author: Coursaget P Lesage G Simpson B Mayelo V Le Cann P.
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Abstract: Incidence of hepatitis C virus infection in burn patients: detection of anti-C100, anti-C33c and anti-Core antibodies. Coursag et P, Lesage G, Simpson B, Mayelo V, Le Cann P. Institut de Virologie de Tours, Facult? de Pharmacie, France. Anti-hepati tis C virus antibodies were searched for in 45 burnt patients, at the time of burn injury and more than 6 months after burn injury. HCV infection was detected in 18% as a consequence of the numerous transfusions of blood or blood derivatives used during the post-burn treatment. Five patients displayed evidence of anti-C100, anti-C33c and anti-Core antibodies together; two patients had only anti-C100 and anti-C33c antibodies, and the last one showed only anti-Core antibodies. Chronic hepatitis was observed in 83% of HCV infections. Kinetics of appearance of anti-HCV antibodies varied between patients. Anti-Core is generally the first to be detected at high levels; however, in at least one case it was detected only two and a half months after C100 and C33c antibodies. PMID: 1668142 [PubMed - indexed for MEDLINE]
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