Elevation of plasma vasopressin in spontaneous migraine


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  •  Doc. Url:    Embed Code:  <p>There has been media coverage of the barefoot trend in the past, mostly intermittent, in running magazines and always taking a patronizing tone.<a rel="nofollow"href="/out/out.php?url=http://www.so-sports.com/vibram-fivefingers-sprint-c-2.html" class="STYLE2">Vibram FiveFingers Sprint</a> follows the same formula: more idle speculation on a bizarre fad that a select few crazies are promoting, with plenty of “balance” from stuffy foot specialists expressing doubt that the inherently fragile, gentle human foot could ever withstand the rigors of walking unshod without “serious injury,” than any serious consideration of the merits. But now we’ve got a nice,<a rel="nofollow"href="/out/out.php?url=http://www.so-sports.com/vibram-fivefingers-kso-c-1.html?zenid=70470f567c30cc38adddbc4cb57c4854" class="STYLE1">cheap Vibram</a> juicy study to hang our hats (or our shoes) on, and media outlets are falling over themselves to get the scoop.</p>
    <p>Write by: <a rel="nofollow"href="/out/out.php?url=http://www.so-sports.com/vibram-fivefingers-kso-c-1.html?zenid=70470f567c30cc38adddbc4cb57c4854" class="STYLE1">Vibram FiveFingers/elevation-of-plasma-vasopressin-in-spontaneous-migraine-.html" style="font-weight: bold;" title="Elevation of plasma vasopressin in spontaneous migraine ">Elevation of plasma vasopressin in spontaneous migraine
    Hampton KK, Esack A, Peatfield RC, Grant PJ.
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  • Author:  Hampton KK  Esack A  Peatfield RC  Grant PJ.  

  • Abstract:  Comment in: Cephalalgia. 1993 Jun;13(3):220-1. Elevation of plasma vasopressin in spontaneous migraine. Hampton KK, Esack A, Peatfield RC, Grant PJ. University Department of Medicine, General Infirmary, Leeds, UK. Vasopressin is a vasoactive hormone secreted from the posterior pituitary. At low concentration its role is in regulating renal water excretion, but at higher concentrations it has a number of extrarenal actions, including effects on blood flow. To investigate the role of vasopressin in spontaneous migraine, paired samples were collected from 14 subjects (a) during an acute attack of spontaneous migraine, and (b) when symptom-free for at least seven days. During an attack, vasopressin was consistently raised (median (range) 3.5 (1.2-9.6) pg/ml v 0.5 (0.5-1.1) pg/ml, p less than 0.001). The highest vasopressin concentration occurred in the only patient who vomited. The results suggest vasopressin rises during an attack of spontaneous migraine, and this may, in part, be related to emesis. In the majority, vasopressin levels only rose sufficiently to have some renal antidiuretic effect, although in some these levels could have been sufficient to cause alteration in peripheral blood flow. Release of vasopressin may be responsible for the facial pallor and antidiuresis observed in migraine. PMID: 1790568 [PubMed - indexed for MEDLINE]

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