Immunogenicity of reduced antigen content tetanus-diphtheria-acellular pertussis vaccine in adolescents as a sixth consecutive dose of acellular pertussis-containing vaccine.
Related Videos
-
Climate Summit - Reduced expec...
-
The UN climate conference in Copenhagen last year was a huge disappointment. What can be expected fr...
-
Equal rights for passengers wi...
-
The 2008 selection of ten success stories where EU action has led to tangible results in the everyda...
Related Hubpages
-
PubMed
(0) (0 Votes)Views: (2) Date: (2007-6-23) Pages: () -
Author: Leonard R Friedland
-
Abstract: Three hundred and nineteen adolescents aged 10-12 years who had been previously vaccinated with five doses of acellular pertussis-containing vaccines received single doses of Tdap (reduced-antigen-con tent tetanus, diphtheria, acellular pertussis) and hepatitis A vaccines in a double-blind crossover trial. Long-term antibody persistence following vaccination with Tdap at pre-school age was similar to that following vaccination with DTaP (diphtheria-tetanus- acellular pertussis). After the sixth dose booster, Tdap induced a vigorous immune response, consistent with protection against diphtheria, tetanus and pertussis diseases.
Related Documents
Related Groups
Related Science News
More on Sciencestage
Answers
- Resolved Question: What are the reasons underlying the poor immunogenicity of many candidate tumor antigens in cancer v…
- Resolved Question: the molecules which can invoke immunogenicity are called?
- Resolved Question: What's the difference between antigenicty and immunogenicty?
...generate an antibody against it" while immunogenicity means "can raise antibodies... - Undecided Question: I need anatomy and Physiology help?
...NOT true of antigens? A. They have immunogenicity; they can provoke immune responses... - Resolved Question: Science Homework Help about vaccines.?
... in trials to assess immunogenicity and protection. of particular interest are... - Resolved Question: About vaccines!?
... in trials to assess immunogenicity and protection. of particular interest are... - Resolved Question: Why do creationists come crawling back to evolution when they need medicine?
...Ahn G, et al. (2001). "Safety and immunogenicity of attenuated dengue virus... - Resolved Question: ♥PLEASE♥ JUST SIMPLE 4 BIO QUESTIONS~ HELP ME!!♥?
...histocompatibility B. immunity C. hematopoiesis D. immunogenicity E. all of the choices are...
News
- Immunogenicity and Tolerability of Recombinant Serogroup B Meningococcal Vaccine Administered With or Without Routine ...
Context In the absence of an effective vaccine, serogroup B Neisseria meningitidis (MenB) remains a major cause of invasive disease in early childhood in developed countries. Objective To determine the immunogenicity and reactogenicity of a multicomponent MenB vaccine (4CMenB) and routine infant vaccines when given either concomitantly or separately. Design, Setting, and Participants Phase 2b ... - BiondVax´s Universal Flu Vaccine Improves Existing Flu Vaccines in Elderly. In a Second Phase II Trial, the Vaccine ...
NES ZIONA, Israel, February 16, 2012 /PRNewswire/ BiondVax´s Multimeric-001 Universal Influenza Vaccine successfully meets primary and secondary endpoints, demonstrating excellent safety and immunogenicity in 120 elderly (65+) participants. … - Phase 3 Data on HEPLISAV(TM) in Adults Aged 18-55 Published in VACCINE
BERKELEY, CA-- - Dynavax Technologies Corporation announced today that results of a pivotal Phase 3 trial of HEPLISAV were published online in the journal VACCINE. Data from this study will be used to ... - Scientific considerations for complex drugs in light of established regulatory guidance
( New York Academy of Sciences ) The FDA is currently working toward implementing the Biologics Price Competition and Innovation Act of 2009. The yet-to-be finalized pathway raises questions that are far more complicated than those posed by traditional, small molecule generics including what type of pre-clinical/clinical data, safety, purity, immunogenicity and potency testing will be required ... - Amicus Therapeutics Awarded Grant From Muscular Dystrophy Association for Pompe Disease Program
CRANBURY, N.J. -- Amicus Therapeutics , a biopharmaceutical company at the forefront of therapies for rare and orphan diseases, today announced the receipt of a two-year, $186,000 grant from the Muscular ... - Immunovaccine to Advance Biodefense Vaccines in a NIH Funded Study
HALIFAX, NOVA SCOTIA-- - Immunovaccine Inc. announced today it has entered into a research collaboration to advance the development of next generation biodefense vaccines against the most threatening biological ... - Effective glycoconjugate vaccines against
Neisseria meningitidis serogroups A, C, W-135, and Y have been developed, but serogroup B remains a major cause of severe invasive disease in infants and adolescents worldwide. We assessed immunogenicity and tolerability of a four-component vaccine (4CMenB) in adolescents. - This Week in JAMA [This Week in JAMA]
Serogroup B Neisseria meningitidis (MenB) is a major cause of disease in early childhood. - Press Release
Glycosylation is important because it can influence the therapeutic efficacy, immunogenicity, solubility, and in-vivo half life of the glycoprotein. A major obstacle in the pharmaceutical application of glycoproteins is the inherent heterogeneity of their glycan structures. - Pivotal study published in JAMA confirms potential of Novartis candidate vaccine Bexsero® to help protect infants ...
Data previously presented at ESPID annual meeting add to the body of evidence showing that Bexsero can help protect all vulnerable age groups Study including more than 1,800 infants showed Bexsero induces ...
Related on Wikipedia
- Immunogenicity - Wikipedia, the free encyclopedia
Immunogenicity is the ability of a particular substance, such as an antigen or epitope, to provoke an immune response in the body of a human or animal. - Antigen - Wikipedia, the free encyclopedia
An antigen is a foreign molecule that, when introduced into the body, triggers the production of an antibody by the immune system. The immune system will then kill or ... - Vaccine - Wikipedia, the free encyclopedia
A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and ... - PEGylation - Wikipedia, the free encyclopedia
PEGylation is the process of covalent attachment of polyethylene glycol polymer chains to another molecule, normally a drug or therapeutic protein. - Proinsulin - Wikipedia, the free encyclopedia
Proinsulin is the prohormone precursor to insulin made in the beta cells of the islets of Langerhans, specialized regions of the pancreas. In humans, proinsulin is encoded by ... - Toxoid - Wikipedia, the free encyclopedia
A toxoid is a bacterial toxin (usually an exotoxin) whose toxicity has been weakened or suppressed either by chemical (formalin) or heat treatment, while other properties ... - Malaria vaccine - Wikipedia, the free encyclopedia
Malaria vaccines are an area of intensive research. However, there is no effective vaccine that has been introduced into clinical practice. The global burden of P. falciparum ... - Conjugate vaccine - Wikipedia, the free encyclopedia
A conjugate vaccine is created by covalently attaching a poor (polysaccharide organism) antigen to a carrier protein (preferably from the same microorganism), thereby ... - Cervarix - Wikipedia, the free encyclopedia
Cervarix is a vaccine against certain types of cancer-causing human papillomavirus (HPV). Cervarix is designed to prevent infection from HPV types 16 and 18, that cause about ... - Neisseria - Wikipedia, the free encyclopedia
The Neisseria is a large genus of commensal bacteria that colonize the mucosal surfaces of many animals. Of the 11 species that colonize humans, only two are pathogens.