Feulgencytophotometric DNA distribution patterns of well-differentiated (mature) and undifferentiated (less mature/immature) forms of primary skin-reticulosis

Abstract:  33 tissue sections of cases of primary skin-reticulosis showing different degrees of maturity were analysed by means of Feulgen-cytophotomet ric methods in regard to their DNA-content. The measurements performed disclosed cytophotometric differences of DNA distribution patterns between mature and less mature/immature forms: Mature forms of reticulosis were characterized by predominantly diploid DNA distribution patterns, whereas less mature/immature forms showed a main distribution in the hyperdiploid-hypotet raploid range respectively atypically dispersed aneuploid values with increase of variation and mean DNA-content. Moreover in several cases distribution patterns were seen, which may be regarded as cytophotometric transition forms showing a diploid peak and a higher rate of cells with enhanced DNA-content. Those cases appeared histomorphologically mature with a slight tendency to immaturity.