Amino acid misincorporation during high-level expression of mouse epidermal growth factor in Escherichia coli

Department of Organic Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark.

Department of Organic Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark.

Erratum in: Cancer Chemother Pharmacol 1992;30(2):164. Affinity of antineoplastic amino acid drugs for the large neutral amino acid transporter of the blood-brain barrier. Takada Y, Greig NH, Vistica DT, Rapoport SI, Smith QR. Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892. The relative affinity of six anticancer amino acid drugs for the neutral amino acid carrier of the blood-brain barrier was examined in rats using an in situ brain perfusion technique. Affinity was evaluated ...

Department of Neuroanatomy, Max-Planck-Institut f?r Hirnforschung, Frankfurt, F.R.G.

Department of Neuroanatomy, Max-Planck-Institut f?r Hirnforschung, Frankfurt, F.R.G.

Enzymatic activity of poliovirus RNA polymerase mutants with single amino acid changes in the conserved YGDD amino acid motif. Jablonski SA, Luo M, Morrow CD. Department of Microbiology, University of Alabama, Birmingham 35294. RNA-dependent RNA polymerases contain a highly conserved region of amino acids with a core segment composed of the amino acids YGDD which have been hypothesized to be at or near the catalytic active site of the molecule. Six mutations in this conserved YGDD region of the poliovirus RNA-dependent RNA polymerase were ma...

A comparative study of the neutrophil stimulatory activity in vitro and pro-inflammatory properties in vivo of 72 amino acid and 77 amino acid IL-8. Nourshargh S, Perkins JA, Showell HJ, Matsushima K, Williams TJ, Collins PD. Department of Applied Pharmacology, National Heart and Lung Institute, London, England. IL-8, a potent neutrophil-activating protein, can be produced by many cell types including monocytes, lymphocytes, fibroblasts, neutrophils, and endothelial cells. Depending on the cell source, the N-terminal amino acid sequence of I...

Laboratory of Human Nutrition, Massachusetts Institute of Technology, Cambridge.

L-[alphaS,5S]-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (NSC-163501), an antibiotic elaborated by Streptomyces sviceus, has been shown to be a powerful inhibitor of many mammalian and bacterial reactions involving the transfer of nitrogen from the gamma-carboxamide of L-glutamine. Thus, the utilization of L-glutamine for the synthesis of carbamyl phosphate, L-asparagine, guanosine-5'-monophosphate, cytidine-5'-triphosphate, N-formylglycinamidine ribonucleotide, NAD, glucosamine-6-phosphate, and anthranilic acid is strongly or tota...

Laboratory of Human Nutrition, Massachusetts Institute of Technology, Cambridge.

of amino acids but many of the amino acids are ones that have never been detected in a simulated ear...

antiparallel. The amino acid side chains from each strand alternately extend above and below the she...

amino acid side chains in the enzymes active site: glutamate 35 and aspartate 52. The highlighted gr...

From Chicago - According to research in the journal Circulation, glutamic acid may help lower blood ...

, forming a five-membered ring that includes the backbone nitrogen. This geometry severely limits th...

, another founder of molecular genetics. 30 minutes. Winner of the Chris Award for Science and Techn...

, another founder of molecular genetics. 30 minutes. Winner of the Chris Award for Science and Techn...

, another founder of molecular genetics. 30 minutes. Winner of the Chris Award for Science and Techn...

, another founder of molecular genetics. 30 minutes. Winner of the Chris Award for Science and Techn...

Lecture Series on BioChemistry I by Prof.S.Dasgupta, Dept of Chemistry, IIT Kharagpur. For more deta...

In enzymology, a bile acid-CoA:amino acid N-acyltransferase ...

thumbnail|300px|The general structure of an α-amino acid, w...

In enzymology, a D-amino-acid transaminase () is an enzyme t...

A glucogenic amino acid is an amino acid that can be convert...

A ketogenic amino acid is an amino acid that can be converte...

In enzymology, an amino-acid racemase () is an enzyme that c...

In enzymology, a D-amino-acid N-acetyltransferase () is an e...

Proteinogenic amino acids are those 22 amino acids that are ...

An essential amino acid or indispensable amino acid is an am...