Mechanisms of tandem duplication in the Duchenne muscular dystrophy gene include both homologous and nonhomologous intrachromosomal recombination

Abstract The well known Vickrey-Clark-Groves (VCG) mechanism provides socially optimal solutions for many allocation problems with strategic buyers, but for divisible goods the bids are infinite dimensional. F.P. Kelly and his co-workers developed an allocation mechanism based on one dimensional bids, which is socially optimal if the buyers are price-takers. The idea is that the one-dimensional bid from a buyer specifies a surrogate valuation function. We propose the VCG-Kelly mechanism, which is obtained by composing the one-dimensional signa...

The Deese/Roediger-McDermott paradigm can produce high levels of false remembering for lists of both semantic and phonological associates. The present study investigated whether similar mechanisms mediate false memories with these two types of lists. Experiment 1 measured the relationship between levels of false memory obtained with lists of semantic and phonological associates. The results indicated little correlation between false memories generated with the two types of associates. Experiment 2 used a between-subjects design to determine whe...

The results of the vestibular apparatus and cerebellum in orthostatic reflex control are summarized. Mechanisms within the brain which govern circulation reflexes and the consequences of disturbances in their function are also included.

The results of the vestibular apparatus and cerebellum in orthostatic reflex control are summarized. Mechanisms within the brain which govern circulation reflexes and the consequences of disturbances in their function are also included.

The role of peroxidase-mediated bacterial killing by rabbit alveolar macrophages was examined. During 3 h of incubation in vitro, alveolar macrophages ingested and killed greater than 88% of the Streptococcus faecalis, Proteus mirabilis, or Streptococcus pneumoniae present in the incubation mixture. Preincubation of alveolar macrophages with inhibitors of catalase, 3-amino-1,2,4-triazole or sodium nitrite, did not alter their bactericidal potential. Iodination of ingested zymosan particles, a peroxidase-dependent and hydrogen peroxide-dependent...

Background New technologies for the detection of earlystage ovarian cancer are urgently needed. Pathological changes within an organ might be reflected in proteomic patterns in serum. We developed a bioinformatics tool and used it to identify proteomic patterns in serum that distinguish neoplastic from non-neoplastic disease within the ovary. Methods Proteomic spectra were generated by mass spectroscopy (surface-enhanced laser desorption and ionisation). A preliminary ?training ? set of spectra derived from analysis of serum from 50 unaffected ...

Bacterial heat shock proteins promote CD91-dependent class I MHC cross-presentation of chaperoned peptide to CD8+ T cells by cytosolic mechanisms in dendritic cells versus vacuolar mechanisms in macrophages. Tobian AA, Canaday DH, Boom WH, Harding CV. Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA. APCs process mammalian heat shock protein (HSP):peptide complexes to present HSP-chaperoned peptides on class I MHC (MHC-I) molecules to CD8(+) T cells. HSPs are also expressed in prokaryotes and chaperone micro...

Vascular neuroeffector mechanisms. Proceedings of the 7th International Symposium on Vascular Neuroeffector Mechanisms held in Bonn, FRG, July 8 - 11, 1990. [No authors listed] PMID: 1672099 [PubMed - indexed for MEDLINE]

Dissection of murine lymphocyte-endothelial cell interaction mechanisms by SV-40-transformed mouse endothelial cell lines: novel mechanisms mediating basal binding, and alpha 4-integrin-dependent cytokine-induced adhesion. Harder R, Uhlig H, Kashan A, Sch?tt B, Duijvestijn A, Butcher EC, Thiele HG, Hamann A. Department of Immunology, I. Med. Klinik, Universit?tskrankenhaus Eppendorf, Hamburg, Federal Republic of Germany. Lymph node-derived endothelial cells were immortalized by infection with SV40 virus and subclones expressing the marker ME...

Abstract ? Content distribution networks (CDNs) are a popular service for the dissemination of multimedia content over wide areas. The existance of a centralized administrative structure makes them attractive for the commercial distribution of high quality content. By sharing resources, service providers can implement their services more efficiently than a single content provider could establish a distribution structure itself. An efficient operation requires cost estimations that allow service providers to determine the dimensioning of their i...

In this University of Kentucky program, Douglas Kerr, professor of neurology, molecular microbiology...

psychobiographical essays on Robert E. Lee and Lee Harvey Oswald. His current research interest is i...

This is a preview of New Research on Molecular Mechanisms and Prevention of Alzheimer 's Disease by ...

intervention and research in large group ethnic and political conflict. He has publications on narci...

intervention and research in large group ethnic and political conflict. He has publications on narci...

scientific career as a cell biologist. He received his Ph.D. Degree from the University of Virginia ...

Dr. Steven Edelman and Dr. Ian Blumer discuss how technology is changing diabetes management. Artifi...

This is a preview of New Research on Molecular Mechanisms and Prevention of Alzheimer 's Disease by ...

This is a preview of Molecular Mechanisms of Longevity Regulation by Giovanni Scapagnini, MD, PhD at...

This is a preview of Molecular Mechanisms of Longevity Regulation by Giovanni Scapagnini, MD, PhD at...

Flexible mechanisms, also sometimes known as Flexibility Mec...

Extension mechanisms for DNS (EDNS) is a specification for e...

Isolating Mechanisms are features of behavior, morphology, o...

Designing Economic Mechanisms is a 2006 book by economists L...

In materials science, fracture toughening mechanisms are pro...

Disease Models & Mechanisms (DMM) is a monthly peer-reviewe...

Methods have been devised to modify the yield strength, duct...

Association for Machines and Mechanism, India is the Indian ...

IPv6 transition mechanisms are important technologies to fac...