Combination effect on HIV infection in vitro of soluble CD4 and HIV-neutralizing antibodies.


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    • Author:  A Roseto  

    • Abstract:  In combination with HIV gp120 V3-loop antibody, two carbohydrate specific neutralizing antibodies (83D4 and 2G12) had a synergistic neutralizing effect on HIV infection. However, sCD4 and an antibody which blocks gp 120/CD4 binding (1B1) both displayed antagonism.

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