Detection of a soluble serum antigen by a new monoclonal antibody ED8 in patients with breast cancer


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    • Author:  A Roseto  

    • Abstract:  A murine hybridoma, secreting monoclonal antibody ED8, was generated by immunization with the breast cancer cell line H466B. ED8 reacts with a 300 kDa antigen present on H466B cell surface. The antigen can be detected in serum from breast cancer patients, using ELISA and immunoblotting.

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