Negative anion gap in a young adult with multiple myeloma
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PubMed
(0) (0 Votes)Views: (1060) Date: (13-12-08) Pages: () -
Author: Gumprecht T O'Connor DT Rearden A Wolf PL.
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Abstract: A young patient with multiple myeloma was found to have a negative anion gap, with marked asymptomatic hyponatremia. The cause for his negative anion gap is thought to be the myeloma protein, which acts as a cation at physiological pH. Such a hyponatremia responds to reduction in serum concentration of paraprotein and should not be treated by sodium replacement.
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