Naltrexone-induced aversions assessment by place conditioning taste reactivity and taste avoidance paradigms
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PubMed
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Author: Parker LA Rennie M.
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Abstract: Naltrexone-induced aversions: assessment by place conditioning, taste reactivity, and taste avoidance paradigms. Parker LA, Rennie M. Department of Psychology, Wilfrid Laurier University, Waterloo, Ontario, Canada. The reinforcing/aversive properties of various doses of naltrexone (0.01, 1, and 10 mg/kg) were assessed in three experiments that employed place conditioning, taste reactivity, and taste avoidance paradigms. Naltrexone produced a place aversion and a taste aversion, but did not produce aversive taste reactivity responses, even at the highest dose (10 mg/kg) tested. This suggests that drugs that produce a place aversion do not necessarily produce a conditional dislike for a flavored solution with which they are paired. PMID: 1584835 [PubMed - indexed for MEDLINE]
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